Welcome to the Predict a Secondary Structure Web Server

作者：张馨予

The Predict a Secondary Structure server combines four separate prediction and analysis algorithms: calculating a partition function, predicting a maximum free energy (MFE) structure, finding structures with maximum expected accuracy, and pseudoknot prediction. This server takes a sequence, either RNA or DNA, and creates a highly probable, probability annotated group of secondary structures, starting with the lowest free energy structure and including others with varied probabilities of correctness. Other structures are included because the minimum free energy structure may not be the correct one. Note that if SHAPE constraints are specified, the SHAPE constraints are applied to the probability annotated structures. In addition, a second group of SHAPE constrained, SHAPE annotated structures will be generated. This SHAPE structure group is distinct from the probability annotated structure group, and is not probability annotated itself.

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February 14, 2018:
RNAstructure tools have been updated to version 6.0.1 which includes several improvements.
Please contact us with any questions or issues regarding this update.