聚( N -异丙基丙烯酰胺)的制备及应用进展

作者：王韵壹、李英、熊慧卿

聚(N-异丙基丙烯酰胺)的制备及应用进展

摘要: 聚（N-异丙基丙烯酰胺）（PNIPAM）是一种温敏性高分子聚合物，在最低临界溶解温度（LCST）处会发生构象转变。对PNIPAM加以改性，可拓宽温敏性聚合物材料的研究领域，使其在药物负载运输、基因传递、化学分析和表面浸润性等领域发挥更大的应用价值。本文对PNIPAM的活性自由基聚合方法及其应用进展进行了综述，并展望了其发展前景。

English

Progress in Preparation and Application of Poly(N-isopropylacrylamide)

Abstract: Poly(N-isopropylacrylamide) (PNIPAM) is one of the thermally responsive polymers, at the lower critical solution temperature (LCST), it undergoes a conformational transition. Its application in many areas, such as the drug delivery, gene transfer, biochemical analysis and so on can be widened by modification. In this article, the research progress in preparation and application of PNIPAM were reviewed, and the prospects of this field were also put forward.