植物AP2/ERF转录因子家族的研究进展

作者：张馨予

摘要： 作为植物最大转录因子家族之一,AP2/ERF转录因子广泛存在于植物中,并因其在基因育种等方面具有重要作用而倍受关注。AP2/ERF转录因子家族成员至少含有一段60个左右氨基酸构成的AP2保守结构域,根据结构域的数量和识别序列的不同可以将其分为AP2、ERF、DREB、RAV和Soloist 5个亚家族,且在拟南芥、水稻、玉米和番茄等植物中,AP2/ERF转录因子及其各个亚家族成员的数量各不相同。研究发现,AP2/ERF转录因子可通过响应乙烯、细胞分裂素和生长素的调节从而直接或间接参与种子发育过程、花和果实等器官的形态建成等植物发育的多个进程;除了初生代谢,AP2/ERF转录因子还在植物次生代谢尤其是在调控药用植物主要药用活性成分（如青蒿素、紫杉醇和木质素）合成方面效果显著。同时,有报道称拟南芥AP2/ERF基因具有正向调节抗灰霉病的功能,一些AP2/ERF基因也被报道在植物应对高盐、干旱、缺氧、低温等非生物胁迫方面具重要功能;另外,AP2/ERF类转录因子还参与了乙烯等介导的非生物信号传导。介绍AP2/ERF转录因子的结构分类特征、在不同植物中的数量分布,并阐述其在植物发育、次生代谢、生物与非生物胁迫和信号传导等方面的研究进展,以期为培育出兼具高产、抗病的实用型转基因作物提供理论依据。

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张麒, 陈静, 李俐, 赵明珠, 张美萍, 王义. 植物AP2/ERF转录因子家族的研究进展[J]. 生物技术通报, 2018, 34(8): 1-7.

ZHANG Qi, CHEN Jing, LI Li, ZHAO Ming-zhu, ZHANG Mei-ping, WANG Yi. Research Progress on Plant AP2/ERF Transcription Factor Family[J]. Biotechnology Bulletin, 2018, 34(8): 1-7.

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